There is a debate about fat-soluble vitamins, the daily requirement and its efficacy to treat diseases or infections. This debate reveals how little is known about fat-soluble vitamins.
A blood test cannot determine the amount of stored fat-soluble vitamins or what are normal levels for these vitamins. Yet, there is evident that people are malnourish. The growing number of people with health problems for industrialized nations highlights the quality differences in the food versus non-industrialized nation. The use of petroleum-based fertilizers disrupts the microbial ecology of the land and the result is a crop that produces lower amounts of minerals and vitamins than the wild-type plant. The U.S. began using this type of fertilizer in 1913. The first sign of a problem was the dust bowl of 1933 but the decrease levels of vitamins in the food was undetected. This problem has been insidious and has increase in severity with each generation because the first dose of fat-soluble and water-soluble vitamins and minerals occurs in the womb and the next dose from breastfeeding thus creating a generational downward step. For perspective, there is the growing number of younger people with health problems, the need for more vaccines in children, and the heavily medicated elderly (critical low levels of fat-soluble vitamins). Tracing the molecular pathway of diseases and infections there is always one or more fat-soluble vitamins involved or rather the under expression of its functions, as in a chronic viral infection (herpes or HIV). As for the debate about an inactive fat-soluble vitamin causing harm, there is no upper limit. The body regulates fat-soluble vitamins intake, metabolism, and storage. To underscore fat-soluble vitamins importance to human health, it drove evolution to develop storage cells because source is seasonal and the environmental factors are constant.
I know of people, after restoring vitamins A and D regulations and reconstitution of storage cells, and water-soluble vitamins and minerals, that have cured insomnia, eczema, psoriasis, herpes, migraine headache, chronic fungal infection and others diseases. The health of any specie depends on the consumption of vital molecules and humans are not exceptional. This basic requirement for the accumulation of vitamins and mineral supports Darwin’s argument, survival of the fit.
Darwin did not know of stem cells when he considered his theory of fitness for survival and reproduction. The greater value of fitness is regeneration and longevity, the gene SIRT1. The activating pathway for stem cells, Wnt/B-catenin, is related to vitamin D and vitamin A respectively. The gene SIRT1, which is linked to longevity, is related to niacin pathway. Evolution intended for fit species to fully utilize stem cells, from the consumption of food that has high vitamins and minerals content and not from the advent of modern medicine.
Reproductive female require a greater amount of vitamin A and D because when a female is pregnant, she must share her stores with the developing fetus. Every aspect of development is dependent upon the metabolism of vitamins and minerals. Nine months later a healthy human is born and is able to survive or fend off microbial organisms. No human should need vaccines. Human evolved in a microbial environment. The immune system, developed over millions of years, can identify and defeat any microbe when it can metabolize vitamin A and D stores for complete eradication.
When every human cell is fully loaded with vitamins and minerals then the specie does not develop cancer. For instance, the area around Chernobyl nuclear accident is seeing a return of land and aquatic life. The animals are normal and flourishing yet, the land is toxic to humans. So why do animals survive from eating the plants? We know that animals of industrialized nations can develop cancer just as humans. The difference is the quality of the food. The system in animals or mammals that remove damage or cancerous cells from the body depends upon the metabolism of vitamin A and D mainly and other vitamins and minerals. The gene that prevents melanoma growth is regulated by vitamin D, and body odor is because of vitamin D deficiency. Evolution did not fail the human specie but rather industrialized agriculture failed to provide humans with the high quality content needed for human health, survival, reproduction, and the evolutionary potential of stem cells.
There was a meeting, at the U.N., of emerging industrialized nations to discuss the growing incidents of diseases and infections, normally found in western civilizations. What this gathering could have discovered is the relationship of food and health. Instead the group found modern medicine. In addition, their livestock and agricultural insects will also suffer with health problems.
In a malnourish society, it is easy to see the ramifications on the physical health. The insidious impact is to mental health. The mental illness of a society affects its citizen in various ways, of which is ones ability to interact with others in forming healthy relationships with spouse, family, and other members of society. Humans are compassionate and a cooperative specie. Yet, if we were only to follow the news or the entertainment community then we will discover the dark side of human behavior or cheaters within a community. When fit, we are better than this and have the potential for greatness: Einstein, Angelo, Bach, and Jobs.
A return to fitness begins with the food, organic farming; the practice of returning valuable nutrients to the soil so that is will produce a nutrient dense crop. However, the process can start with supplementing the food with vitamins and minerals. Vitamin A 25,000 I.U., 6 to 9 per day, vitamin D 5,000 I.U. 6 to 9 per day, zinc 50mg per day(needed to transport vitamin A into the body, metabolism and storage), calcium 1 to 2 grams per day, and total minerals(normally found in natural water and food). Reconstitution of storage cells will take 2 to 3 years because of nine months in the womb and 1 to 2 years of breastfeeding. Restoration of vitamin A and D pathways will take approximately 9 months to a year. Still it is vital to continue for life because life depends upon it.
Fat-soluble vitamins supplements are inactive, as it is in food. Its uptake into the body is regulated and also metabolism and storage.
Future humans may also discover the evolutionary potential of the Homo sapiens brain.