The opposite of life, is odd way of framing the question to me, I would have said “what constitutes life?”
Answering the question the way you framed it; that which is most opposite of life is “nothing” no dimensions, no time, no matter, no energy, “nothing.” That is because “nothing” has none of the characteristics like atoms or energy or dimensions.
To answer the question of what constitutes life; here are the 12 characteristics needed for something to be considered life according to The Scientist: Is it life? (note these characteristics apply only to biological life)
1 membrane enclosures
2 that can capture energy
3 maintain ion gradients
4 encapsulate macromolecules
5 divide
6 Macromolecules must be able to grow by polymerization
7 evolve in a way that speeds growth
8 store information
9 Add to that information store the ability to mutate
10 direct growth of catalytic polymers
11 contain genes and enzymes that can be replicated
12 share genes and enzymes among daughter cells
You could simplify those 12 requirements down to 4 general requirements:
1. environmental barrier
2. metabolism
3. store information
4. evolve
